News

Julia Gagliardi moves from research technician to PhD candidate in the lab

Saloni Patel completes her Master’s

The 22nd International Conference on HTLV, in Philadelphia, hears the lab’s EP300 work in ATLL

An NIH R21 opens the work on HPV DNA structure at sites of integration

R21DE035973, “HPV DNA Structure and Genome Instability at Sites of Integration”, is funded by NIDCR and runs to March 2028.

An invited talk at the University of Pennsylvania on somatic hypermutation in clonal hematopoiesis

At the Center of Excellence in Environmental Toxicology.

An NIH R01 funds five years on EP300 in adult T-cell leukemia

R01CA307099, “Implications of EP300 Deficiency in Adult T-Cell Leukemia/Lymphoma”, was scored in the 4th percentile and runs to March 2031.

Three undergraduate researchers, Mark Youssef, Caroline Mazurek and Anya Kotha, join the lab

Cells opens a special topic on DNA replication defects and genome stability, edited by Advaitha Madireddy

Her second such topic, after “Chromosomal Fragile Sites, Genome Instability and Human Diseases” at Frontiers in Genetics.

Advaitha Madireddy joins NIH oncology fellowship study sections

She has reviewed for Department of Defense peer review panels since 2024.

EP300 deficiency drives chronic replication stress, in Nature Communications

Barreto-Galvez et al., with Advaitha Madireddy as senior and corresponding author.

Paper: EP300 deficiency leads to chronic replication stress mediated by defective replication fork protection

Elevated clonal hematopoiesis in 9/11 first responders, in Cancer Discovery

Paper: Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-related Patterns and Relies on IL1RAP for Clonal Expansion

Aastha Juwarwala leaves the lab after co-authoring two studies

The EP300 paper in Nature Communications and the polymerase η preprint both carry her name.

Advaitha Madireddy speaks at Stanford on EP300 and genome stability

The invited talk was “The Multifaceted Contribution of EP300 in Maintaining Genome Stability”.

Three posters at the Cold Spring Harbor Eukaryotic DNA Replication and Genome Maintenance meeting

On EP300 and fork protection, on a dietary genotoxin for Fanconi anemia patients and on polymerase η recruiting FANCD2.

A preprint from Niljikar and colleagues shows polymerase η recruiting FANCD2 to common fragile sites

Paper: Polymerase Eta Recruits FANCD2 to Common Fragile Sites to Maintain Genome Stability

The lab presents at the Fanconi Cancer Foundation Scientific Symposium for a second year

Charlotte, North Carolina, in 2024, then Orlando, Florida, in 2025.

Archana Pradeep completes an honors thesis in the lab and is a co-author on the EP300 paper

Smrithi Amran begins a Master’s in the lab

Carolina Plasencia takes up a research technician post

Advaitha Madireddy co-directs a new Rutgers graduate course, Molecular Response to Therapeutic DNA Damage

Apeksha Fernandes joins the lab as an undergraduate researcher

The lab’s SMARD protocol is published in STAR Protocols, so other labs can run it

Paper: Visualizing DNA replication by single-molecule analysis of replicated DNA

Mrunmai Niljikar defends her Master’s thesis

Hepatitis B integration patterns in hepatocellular carcinoma, with the Cao lab in Journal of Medical Virology

Paper: Temporal and structural patterns of hepatitis B virus integrations in hepatocellular carcinoma

Mrunmai Niljikar stays on in the lab as a PhD candidate

A new award starts the lab’s work on common food dyes in Fanconi anemia

“Elucidating the Adverse Effects of Common Food Dyes in Fanconi Anemia Patients”, funded by the New Jersey Center for Pediatric Cancer & Blood Disorders Research, runs to June 2024.

Angelica Barreto-Galvez defends the lab’s first PhD dissertation

Aastha Juwarwala joins the lab as a research technician

Rutgers honors Advaitha Madireddy with its Distinguished Rutgers Youth Enjoy Science (RUYES) Faculty Mentor Award

Saloni Patel begins a Master’s in the lab

Ranran Zhang joins as a Research Associate III

She stayed with the lab through October 2023.

Three papers in one fall, in Molecular Cell, Nature Medicine and Blood

The lab takes its work to the Cold Spring Harbor DNA Replication meeting

The New Jersey Commission on Cancer Research backs the PHF6 work in pediatric T-ALL

Pediatric Research Grant COCR22PRG002, “Novel Molecular Mechanisms Dysregulated in the Absence of the PHF6 Tumor Suppressor in Pediatric T-ALL”, runs to June 2025.

SRM University gives Advaitha Madireddy its Distinguished Alumni Award for Academic Excellence

Mrunmai Niljikar starts her Master’s thesis, and Nikita Amin rotates in

The lab’s first paper lands in PNAS: polymerase η at common fragile sites

Paper: Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites

Julia Gagliardi arrives as a Research Teaching Specialist IV

A Department of Defense Idea Award funds the clonal hematopoiesis work

NYU Dental School admits Vasudha Kumar

Angelica Barreto-Galvez passes her qualifying exam

Two technical assistants, Imelda Saintilma and Vasudha Kumar, start

Anam Shaikh and Priyanka Tiwari are both headed to medical school

An NHLBI graduate student supplement funds Angelica Barreto-Galvez; Vasudha Kumar and Rohan Lattupally join

Angelica Barreto-Galvez clears her pre-qualifying exam

Aris Magoulas joins for the summer

Undergraduate intern Kritika Sharma joins the lab

Angelica Barreto-Galvez becomes the lab’s first PhD student, and Thushara Nethramangalath rotates in

The lab’s first postdoctoral fellow, Angelo Mandarino, arrives

Angelica Barreto-Galvez and Anam Shaikh join, four months after the doors opened

An American Cancer Society pilot grant opens the ATLL work

The award is for understanding the mechanisms driving genomic instability in adult T-cell leukemia/lymphoma.